Search results for "Collagen type I hydrogel"

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Bioactive glass ions induce efficient osteogenic differentiation of human adipose stem cells encapsulated in gellan gum and collagen type I hydrogels

2019

Abstract Background Due to unmet need for bone augmentation, our aim was to promote osteogenic differentiation of human adipose stem cells (hASCs) encapsulated in gellan gum (GG) or collagen type I (COL) hydrogels with bioactive glass (experimental glass 2-06 of composition [wt-%]: Na2O 12.1, K2O 14.0, CaO 19.8, P2O5 2.5, B2O3 1.6, SiO2 50.0) extract based osteogenic medium (BaG OM) for bone construct development. GG hydrogels were crosslinked with spermidine (GG-SPD) or BaG extract (GG-BaG). Methods Mechanical properties of cell-free GG-SPD, GG-BaG, and COL hydrogels were tested in osteogenic medium (OM) or BaG OM at 0, 14, and 21 d. Hydrogel embedded hASCs were cultured in OM or BaG OM fo…

SerumAdipose stem cellCompressive StrengthAdipose tissueCell Count02 engineering and technologySpectrum Analysis Raman01 natural sciencesMineralization (biology)Hydrogel Polyethylene Glycol Dimethacrylatelaw.inventionchemistry.chemical_compoundOsteogenesislawOsteogenic differentiationBioactive glassMineralsTissue ScaffoldsbiologyStem CellsPolysaccharides Bacterialbioactive glassCell DifferentiationMiddle Aged021001 nanoscience & nanotechnologyGellan gumCross-Linking ReagentsAdipose TissueMechanics of MaterialsBioactive glassSelf-healing hydrogelsOsteocalcinFemaleStem cellimplantit0210 nano-technologyMaterials scienceCell SurvivalOsteocalcinosteogenic differentiationchemistry.chemical_elementBioengineeringmacromolecular substancesCalciumta3111010402 general chemistryCollagen Type ICollagen type I hydrogelBiokemia solu- ja molekyylibiologia - Biochemistry cell and molecular biologylasiBiomaterialsCalcification Physiologicbiologinen aktiivisuusgellan gum hydrogelAnimalsHumansta217Ionsgeelitta1182adipose stem cellkantasolutRats0104 chemical sciencesDurapatiteGene Expression RegulationchemistryBiophysicsbiology.proteinGlassGellan gum hydrogelluukudoksetcollagen type I hydrogelBiomarkersMaterials Science and Engineering: C
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